Medical Cannabis and Fibrous Dysplasia -Cannabis Being Used To Fight Excruciatingly Symptoms

Fibrous Dysplasia, a rarely occurring disease, is a condition characterized by abnormal growth of fibrous tissue in one or more bones in your body. Fibrous Dysplasia is noncancerous and tends to weaken the affected bone progressively, leading to a greater risk of fractures.

Generally, patients do not experience any symptoms. However, one type of Fibrous Dysplasia brings along severer symptoms and a greater probability of the condition getting diagnosed in time.

Experts believe that natural remedies like cannabis extracts may do wonders to improve the condition of patients and reduce the pace of abnormal tissue growth in the affected regions of the body. Here we closely address various facts about medical cannabis and Fibrous Dysplasia, which may help you understand how fibrous Dysplasia affects you and how cannabis could help with it. Stick around to learn more.

What Is Fibrous Dysplasia?

Fibrous Dysplasia is a benign tumor that affects bones. It makes up only 7% of all the benign tumors that affect bones in human beings. It’s likely to affect any bone of your body. Sometimes it’s a single time; however, it might as well affect multiple bones. The bones most likely to get affected are as follows:

• The thigh bone, also known as the femur
• Tibia
• Skull
• Ribs
• Upper arm bone
• Pelvis

Fibrous Dysplasia is caused by genetic mutations in the body that lead to the growth of an abnormal type of fibrous tissue in the region around the bone. Although it affects children and younger people, it is generally not diagnosed any sooner.

Key Takeaways:

To understand the condition better, here’s a list of all the key points related to fibrous Dysplasia:

• The benign fibrous tissue looks like a “scar.”
• Usually, children between the ages of 3 to 15 tend to get affected by Fibrous Dysplasia.
• Although experts are still trying to figure out the main causes, it has been found that it’s not affected by hereditary factors.
• Affected individuals may have to face symptoms such as pain and deformity.

What are the symptoms of Fibrous Dysplasia?

For many patients, fibrous Dysplasia remains undiagnosed, as there are barely any noticeable symptoms for quite some time. Especially if the patient’s condition is mild, it’s harder to notice any visible signs or symptoms, which keeps them in the grey area for a long time. Patients with severe fibrous Dysplasia may experience the following symptoms, varying from individual to individual.

• The most prominent symptom in patients with fibrous Dysplasia is bone pain. It must be noted here that the pain is not pinching at all. It’s a dull pain varying in intensity from mild to moderate.
• Inflammation is another common symptom caused by the inflammatory response of the body.
• Patients are quite likely to experience bone deformity.
• Fibrous Dysplasia makes you quite vulnerable to bone fractures that typically affect regions including arms and legs.
• The curvature of the bones of the legs.
• In case jaw bones get affected, you may experience nasal congestion, bulging eyes, uneven jaws, and other symptoms.
• At times the tissue may compress the nearby nerves, leading to other symptoms, such as impaired hearing and loss of vision in case skull bones are affected.

You may get any bone affected. However, the most commonly affected bones in most cases are the femur, tibia, humerus, skull, pelvis, and rib bones. In some cases, Fibrous Dysplasia is associated with the condition that typically attacks your endocrine system, which may ultimately lead to the following complications:

• Early commencement of the puberty
• Excessive hormone production
• Spotty skin
• Alterations in the normal menstrual cycle or pregnancy

Causes:

Fibrous Dysplasia finds its links with genetic mutations. Experts believe that a gene mutation in certain bone-producing cells ultimately leads to fibrous Dysplasia. Consequently, irregular and immature bone tissue is formed. Typically this lesion is produced on one particular region of a certain bone, which means that only one bone is affected at a time.

However, some cases involve multiple bones getting affected at the same time. In such a case, mutations result in lesions on different bones at several sites. As the individuals hit puberty, the growth of these lesions ceases. However, it’s quite likely to start over sometime during the pregnancy, posing certain additional threats.

Also, experts found that hereditary factors barely play any roles in the development of this condition. Therefore neither can you acquire fibrous Dysplasia through genes nor pass it on to your offspring.

Risk Factors:

Well, Fibrous Dysplasia isn’t a common disease. It rarely occurs and prevails for the whole lifetime of the individuals. The factors that add to your vulnerability to develop fibrous Dysplasia are still under research and not really found by the experts. However, age is considered an important factor as individuals are more likely to get affected during childhood and young age.

Types of Fibrous Dysplasia;

Based on the extent of effects caused by the condition, Fibrous Dysplasia is categorized into two main types to understand them further. As soon as a patient successfully figures out what type of fibrous Dysplasia he’s going through, it’s much easier to get treatment accordingly. Following are the two main types of fibrous Dysplasia.

• Monostotic Fibrous Dysplasia:

This kind of fibrous Dysplasia is characterized by a condition where only one of the bones in your body is affected. This is reported as the most commonly occurring type in the patients, about 7 cases in every 10 fall under this category. According to the observed pattern of this type of fibrous Dysplasia, generally, the skull is the most affected part.

• Polyostotic Fibrous Dysplasia:

This type of fibrous Dysplasia involves effects on at least two or more bones of the body. In some cases, several bones are affected in the same limb, while in others, various bones are affected in different body parts. This type generally involves severer symptoms as compared to monostotic Fibrous Dysplasia. Severe symptoms lead to a quicker diagnosis, which is a blessing in disguise for the patients as they can get treatment in time.

Medical Cannabis and Fibrous Dysplasia: How Cannabis Helps?

Cannabis is a whole new world of curative cannabinoids, terpenes, and flavonoids. The most common cannabinoids are CBD, CBN, CBG, THC, and CBC. These cannabinoids can be used isolated or combined. Using cannabis extract as a whole may help you experience the entourage effect of all the components, which enables you to fight excruciating symptoms of various medical conditions. It can be incorporated into the body through multiple modes of administration as per your preference and convenience.

Experts believe that cannabis and Fibrous Dysplasia might make a harmonious match together. To help the patients live better, cannabis introduces several alterations in the working mechanisms of the body to improve the severity of symptoms. Here’s how cannabis can help you lead an easier life as a Fibrous Dysplasia patient:

• It’s Easier To Endure The Pain:

Pain, the primary concern for fibrous Dysplasia patients, can cause radiating or throbbing sensations in the bone and neighboring regions. This might make it hard for the patients to cope with day to day challenges of life. Experts suggest medical cannabis may potentially reduce the intensity of pain and weakness of bones. This can substantially facilitate the patients to minimize the level of discomfort and ache.

CBD and THC are known for their marvelous abilities to reduce pain and reduce the risks of side effects generally posed by conventional painkillers.

• Relief From Stiffness

Stiffness is the second most common symptom of the said condition. Even if fibrous Dysplasia itself doesn’t cause stiffness, the surgical procedures used for the treatment might lead to stiffness that may get excruciatingly bad. Experts suggest that cannabis could be used to relieve such pain.

• Better Bone Health

Bone health is a serious concern for patients getting bone fractures due to fibrous Dysplasia. Experts believe that CBD can not only enhance the healing process of bones but also make them stronger than before

How does cannabis work?

Cannabis has cannabinoids that work by interacting with your endocannabinoid system and the Cannabinoid receptors. They can activate your body’s CB1 and CB2 receptors, which ultimately help your body manage chronic pain. In some cases of Fibrous Dysplasia, the pain doesn’t respond to conventional medications but to medical cannabis.

Research on Medical Cannabis and Fibrous Dysplasia

The following research works clearly display how cannabis and fibrous Dysplasia may work together to help the patients:

• Research shows that CBD may promote the maturation process of the collagenous matrix of the bone, which contributes to bone health.[1]
• Another study suggests that cannabis can even address treatment-resistant neuropathic pain. [2]

Final thoughts:

The aspects above of medial cannabis and fibrous Dysplasia potentially support the applicability of cannabis extracts to address symptoms of the said condition.

• https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7340702/
• https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000155/#:~:text=In%20summary%20the%20authors%20concluded,of%20the%20evidence%20is%20poor.